Curative treatment of locally recurrent rectal cancer: is induction chemotherapy warranted?
نویسندگان
چکیده
منابع مشابه
Locally recurrent rectal cancer: treatment options
primary tumor. From 20% to 50% of patients with LR have isolated the local recurrence without distant metastasis. LR may be accompained with pain, bleeding or constipation, depending on the type of the previous surgery. The management of the isolated locoregional recurrence is difficult and treatment options may be limited in patients who have already received a local radiation therapy for the ...
متن کاملIntentionally curative treatment of locally recurrent rectal cancer: a systematic review.
BACKGROUND There is a lack of outcome data beyond local recurrence rates after primary treatment in rectal cancer, despite more information being necessary for clinical decision-making. We sought to determine patient selection, therapeutic modalities and outcomes of locally recurrent rectal cancer treated with curative intent. METHODS We searched MEDLINE (1990-2010) using the medical subject ...
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Developments in chemotherapeutic strategies and surgical technique have led to improved loco regional control of rectal cancer and a decrease in recurrence rates over time. However, locally recurrent rectal cancer continues to present considerable technical challenges and results in significant morbidity and mortality. Surgery remains the only therapy with curative potential. Despite a hostile ...
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The treatment of colorectal cancer, that presents considerable health problem, still has a lot of space for improvement. The overall recurrence rate for this disease is between 8 and 50% according to literature data (Das, Skibber et al. 2006; Kaiser, Kang et al. 2006). The risk for recurrence is highest in the first two years postoperatively (Juhl G 1990; McCall JL 1995; Micev M 2000; Krivokapi...
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Background: Purpose: The purpose of our study is to demonstrate that intensified neoadjuvant chemo-radiotherapy (CRT) treatment in locally advanced rectal cancer (LARC), aimed at further enhancing the complete pathological response and local disease control, is feasible and well tolerated. Materials and Methods: From January 2011 to December 2015, 62 patients (women 21, men 41, mean age 61,5, ...
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ژورنال
عنوان ژورنال: British Journal of Surgery
سال: 2021
ISSN: ['1365-2168', '0007-1323']
DOI: https://doi.org/10.1093/bjs/znab065